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Rosacea Treatment Creams

Erythromycin 250mg Tablets
Pack Size: 168 tablets (6 weeks supply)
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  • The dose of this medicine, how often it is taken and how long it needs to be taken for depends on the type of infection you have, your age and your kidney function. Follow the instructions given by your doctor. These will be printed on the dispensing label that your pharmacist has put on the packet of medicine.
  • Erythromycin is usually taken twice a day (every 12 hours) or four times a day (every six hours), depending on the type of infection being treated. You should try to space your doses evenly throughout the day.
  • Erythromycin can be taken with or without food.
  • If you forget to take a dose take it as soon as you remember, unless it is nearly time for your next dose. In this case leave out the missed dose and just take your next dose as usual. Do not take a double dose to make up for a missed dose.

Erythrocin tablets contain the active ingredient erythromycin, which is a type of medicine known as a macrolide antibiotic. It is used to treat infections caused by bacteria. (NB. Erythromycin is also available without a brand name, ie as the generic medicine.)

Erythromycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. Erythromycin doesn'’t directly kill the bacteria, but leaves them unable to increase in numbers. The remaining bacteria eventually die or are destroyed by the immune system. This treats the infection.

Erythromycin is a broad-spectrum antibiotic that is active against a wide variety of bacteria that cause a wide variety of infections. Erythromycin may be used to treat infections of the upper or lower airways, skin or soft tissue, eyes or ears. It may also be used to treat certain sexually-transmitted infections, oral and dental infections, and to prevent infections in people who are at risk, for example due to surgery, trauma or burns.

Erythromycin is also used for treating inflammatory acne, as it is active against the bacteria associated with acne, Propionebacterium acnes. This is a common type of bacteria that feeds on sebum produced by the sebaceous glands in the skin. It produces waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots. By controlling bacterial numbers, erythromycin brings the inflammation of the sebaceous glands under control, and allows the skin to heal. (Other antibiotics may be preferred for acne however, as strains of the Propionebacterium that are resistant to erythromycin are becoming widespread.)

To make sure the bacteria causing an infection are susceptible to erythromycin your doctor may take a tissue sample, for example a swab from the throat or skin.

Erythromycin has a similar range of antibacterial activity to penicillin and so is also useful as an alternative to penicillin in people who are allergic to penicillins.



Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

  • Nausea and vomiting.
  • Abdominal pain.
  • Diarrhoea.
  • Allergic skin reactions, such as rashes, hives or itching.
  • Disturbances of liver function.
  • Inflammation of the liver (hepatitis).
  • Yellowing of the skin and eyes (jaundice).
  • Inflammation of the pancreas (pancreatitis).
  • Reversible hearing loss (usually only after large doses).
  • Abnormal heart beats (arrhythmias).
  • Inflammation of the large intestine (colitis) - see warning section above.

Prolonged treatment with antibiotics can sometimes cause overgrowth of other

  • Unless your doctor tells you otherwise, it is important that you finish the prescribed course of this antibiotic medicine, even if you feel better or it seems the infection has cleared up. Stopping the course early increases the chance that the infection will come back and that the bacteria will grow resistant to the antibiotic.
  • Broad-spectrum antibiotics can sometimes cause inflammation of the bowel (colitis). For this reason, if you get diarrhoea that becomes severe or persistent or contains blood or mucus, either during or after taking this medicine, you should consult your doctor immediately.

Use with caution in

  • Decreased liver function.
  • Severely decreased kidney function.
  • Abnormal heart rhythm seen on a heart monitoring trace (ECG) as a 'prolonged QT interval', or people at risk of this (your doctor will know).
  • Abnormal muscle weakness (myasthenia gravis).
  • Hereditary blood disorders called porphyrias.
Mirvaso Gel
Pack Size: 30g
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One application per 24 hours, at any time suitable for the patient, for as long as facial erythema is present. The maximum daily recommended dose is 1g in total weight. Mirvaso should be applied smoothly and evenly as a thin layer across the entire face avoiding the eyes, eyelids, lips, mouth and membrane of the inner nose. Mirvaso should only be applied over the face. Wash your hands immediately after applying. 
Mirvaso can be used in conjunction with other cutaneous medicinal products for the treatment of inflammatory lesions of rosacea and with cosmetics. These products should only be applied immediately before the daily application of Mirvaso, they may be used only after the applied Mirvaso has dried.

Mirvaso gel is used for the topical treatment of persistent facial erythema of rosacea in adults of 18 years and over. Each one gram of gel contains 3.3mg of Brimonidone, equivalent to 5mg of Brimonidine Tartrate.

Rosacea is a very common skin condition that affects many millions of people in the world. People over the age of 30 are more likely to get rosacea.

Like all medicines, Mirvaso can cause side effects, although not everybody gets them. Side effects that are considered to be common include redness, itching, flushing and skin burning sensation, all occurring in 1.2 to 3.3% of patients in clinical studies. They are typically mild to moderate in severity, and usually do not require Mirvaso use to be stopped. These side effects can feel like a worsening of your initial symptoms, and it is impossible to predict if you will experience them before you try Mirvaso. For this reason, we recommend that you order just one tube to start with, and use the gel on a small area of the face at first. Unfortunately we are not able to offer a refund for the product if you experience this common and documented side effect.

Keep out of the reach and sight of children. Not to be used in children less than 18 years. Do not use if you are allergic to any of the listed ingredients. Do not apply to closed eyes. Mirvaso has not been studied in patients with renal or hepatic impairment. Mirvaso should not be used during pregnancy or breast feeding.

Rozex 0.75% Gel
Pack Size: 40g
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First wash and dry the affected areas of your skin. Apply a thin layer of the gel to all the affected areas. Rub the gel well in. Always replace the cap and wash your hands after use. Your gel should be used in this way twice a day, (morning and evening), or as advised by your doctor.

Rozex gel contains the active ingredient Metronidazole and is used to treat rosacea. Rozex helps to treat pimples, pustules (spots) and redness found with rosacea. Metronidazole belongs to a group of medicine called Antiprotozoal and antibacterial agents and has been shown to help to control infection and inflammation in certain skin problems, such as rosacea.

Keep out of the reach and sight of children. Do not use if you are allergic to any of the ingredients. Do not use if you suffer from any blood disorders and not to be used on children. Do not go out in strong sunlight and avoid exposure to ultra violet light whilst using Rozex . If pregnant or breast feeding it is not advisable to use this product.

About Rosacea

Rosacea Background

Rosacea is a very common skin complaint that mainly affects the face. The condition will present as the skin becoming red for short periods, this can also referred to as flushing. Other associated symptoms can include:

  • Permanent redness
  • A burning or stinging sensation
  • Spots
  • Small blood vessels can become visible in the skin

Rosacea is a condition that is prone to relapsing. This means you will experience episodes of severe symptoms that will be followed by periods where the condition is less severe. An episode of rosacea can be triggered by numerous factors, with different people having different triggers. The most triggers are:

  • Exposure to hot or cold temperatures
  • Strong winds
  • Alcohol, caffeine and hot drinks
  • Spicy food and dairy products
  • Sunlight exposure
  • Stress
  • Humidity
  • The menopause

It isn’t fully understood what exactly causes rosacea. There are a number of possible factors that have been suggested. It is believed by some experts that rosacea is caused by a blood vessel abnormality. However, what causes this particular abnormality is still unknown.

More recent research has suggested that the external triggers of rosacea can lead to the activation of molecules in the skin known as peptides. Having excess levels of peptides in the skin can activate both the immune and neurovascular systems of the skin. This activation can cause the blood vessels to dilate, resulting in redness and inflammation.

Another possible cause are microscopic mites called demodex folliculorum. These mite usually reside harmlessly on human skin. Sufferers of rosacea present with higher numbers of these mites and research suggests rosacea can be caused by the skin’s reaction to the bacteria found in the mite’s faeces.

Alternatively, a current theory suggests that a bacteria found in the digestive system, helicobacter pylori bacteria, is the cause of rosacea. This theory argues that helicobacter pylori stimulates the production of a protein called bradykinin. This protein is known to cause blood vessels to expand and hence cause the effects of rosacea.

It is apparent that rosacea is more common in families. This could suggest a genetic cause of the condition. However, it is not clear which genes are involved or how the condition is passed on.

Rosacea Symptoms

The main and most common symptom of rosacea is facial flushing. This is characterised by the skin turning red for short periods-usually only a few minutes. This flushing will mainly affect the face but in some instances the neck and chest can be affected as well. Some sufferers experience an uncomfortable heat sensation that accompanies this skin reddening.

Some sufferers are affected by a persistent facial redness that resembles a patch of sunburn that does not subside. This form of rosacea is known as erythema and it usually affects the nose, cheeks and chin. In some cases erythema can spread to the forehead, neck and chest.

Another visible symptom of rosacea can include permanently widened blood vessels. These vessels have dilated over time and will be visible on the skin. This is known as telangiectasia.

Someone with rosacea can develop papules and pustules. A papule is a round red bump that protrudes from the skin. A pustule is a puss-filled swelling. These will mainly appear on the face and can resemble the symptoms of acne. However, rosacea and acne are unrelated conditions. Unlike acne, rosacea does not potentially damage the skin or cause any scarring.

In more severe cases of rosacea the skin can thicken, causing the sufferer to experience a build-up of excess tissue. This tissue usually forms around the nose causing it to become enlarged and bulbous. This symptom will take years to develop and is not that common. This thickening of the skin is called rhinophyma and tends to affect more men than women.

Rosacea can, in some cases, affect the eyes as well. This is known as ocular rosacea and symptoms can include; dry, irritated or bloodshot eyes, inflammation of the eyelids and feeling as though there is something in your eyes. If ocular rosacea starts to cause any pain in the eye, blurred vision or a sensitivity to light then it is recommended to seek medical advice immediately.

Other more generic symptoms associated with rosacea include:

  • Lymphoedema: A swelling of the face.
  • Rough, dry skin.
  • Sensitive skin that can include; burning, stinging, itching and pain.

Rosacea Diagnosis

Rosacea can be diagnosed by a doctor or dermatologist by a visual inspection and through questions about your symptoms and triggers.

Rosacea Treatment

Unfortunately, rosacea doesn’t have a cure. However, there are treatments available designed to keep the symptoms contained. The type of treatment will depend on what symptoms you are presenting with. If your rosacea has caused papules and pustules to develop then there are various different treatments that can be effective.

The first line of treatment will usually be a topical gel or cream. The two topical treatments most often prescribed are Metronidazole (Rozex Gel) and Azelaic Acid (Skinoren Cream). Treatments such as Skinoren and Rozex are usually applied once or twice daily to the affected area. If Skinoren and Rozex have proved ineffective then a course of oral antibiotics may be necessary. Antibiotics used to treat rosacea include Tetracycline, Oxytetracycline and Erythromycin. These courses usually last for four to six weeks, depending on the persistence of the spots.

Treating facial redness in rosacea can prove more difficult to treat than papules and pustules. Brimonidine Tartrate (Mirvaso Gel) is a topical gel treatment that works by restricting the dilation of the blood vessels in the face. Research shows it can have an effect in as little as 30 minutes after application. Once applied the effects of Mirvaso Gel can last for up to twelve hours.

Treating thickened skin (rhinophyma) will require referral to a dermatologist or plastic surgeon. There are a number of surgical treatments available that can remove the excess tissue from the nose.

Treating ocular rosacea may require lubricating eye drops or oral antibiotics from your GP. If these prove ineffective then you will need to be referred to an ophthalmologist for further testing and treatment.

Rosacea Prevention

There are a number of self-help techniques that can help contain the symptoms of rosacea. These involve:

  • Avoiding known triggers: For example, if you know hot baths trigger your rosacea then try reducing the water’s temperature or have a cooler shower instead. If sunlight makes your symptoms worse then reduce exposure by covering the skin or by using a sensitive, high SPF sunscreen. Stress is a very common trigger of rosacea. By managing your stress levels you can help reduce the chance of an outbreak.
  • Looking after your skin: Cleanse and moisturise your skin using non-irritant, hypoallergenic products designed for sensitive skin. It is recommended to avoid astringent toners and products that contain ingredients that can cause irritation to the skin. Known irritants include; fragrances, alcohol, menthol, lanolin, clove oil, witch hazel, eucalyptus oil, sodium lauryl sulphate and camphor. For men, switching to an electric razor has been shown to reduce skin irritation.
  • Using camouflage make-up: If suffering with persistent red skin then using suitable make-up products will help to conceal these patches. Your GP or specialist can refer you to a skin camouflage service or directly prescribe skin camouflage products.
  • Keeping your eye lids clean: If rosacea is known to affect you eyelids then ensure they are kept clean. This will help reduce any inflammation or irritation. If using eye make-up, it is recommended to select a product that is mild and washes off easily.

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THE Medical Online Doctor service is owned and operated by Total Health Ethos Limited (Company Reg. 6170784). All orders are fulfilled by our pharmacy partners, BSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products. For more information see our policies and terms and conditions at the bottom of every page. © 2017 Total Health Ethos Limited. All rights reserved.
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