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Malaria Prevention Tablets (Antimalarials)

Atovaquone/Progaunil 250mg/100mg Tablets (Generic Malarone)
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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  • You should take one tablet every day at roughly the same time each day.
  • Atovaquone/Proguanil tablets need to be taken 2 – 3 days before entering an area where malaria is present and continued until 7 days after leaving the malaria area.
  • You should take Atovaquone/Proguanil tablets with or after food or milk
  • Atovaquone/Proguanil remains effective with a moderate alcohol intake.

Recommended by our Pharmacists & GPs for travellers who require Malarone. Generic Malarone offers the same quality & malaria protection with a significant saving against the branded alternative.

Atovaqoune and proguanil are now available as a generic alternative to Malarone. They are still manufactured to the same high standards as Malarone but are available at a lower cost because the patent has now expired. They are taken once daily, 2 - 3 days before travel and continuing 1 week after returning.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Atovaquone and proguanil should not be taken if you are pregnant or breastfeeding. It is generally very well tolerated with only mild intestinal upsets and headaches reported. If side effects are experienced then taking the tablets with or after a meal may help to relieve them. 

If you do experience side effects from Atovaquone/Proguanil they may include coughing, diarrhea, dizziness, headache, loss of appetite, mouth sores, nausea, stomach pain, vomiting, or weakness. Atovaquone/Proguanil has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Atovaquone/Proguanil should not cause a harmful interaction with any of your other current medicines. Please read the Patient Information Leaflet enclosed with your medicines for further information.

Unfortunately Atovaquone/Proguanil is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods. See the Pharmacist Tips for bite avoidance techniques.

Remember it is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.

Avloclor 250mg tablets
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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Our Price: £9.50
Total trip duration in weeks: In Stock 
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  • You should take two tablets every week on the same day each week.
  • Avloclor needs to be taken one week before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Avloclor with or after food.
  • Avloclor remains effective with a moderate alcohol intake.

Chloroquine is the active ingredient in Avloclor tablets. They are taken as a single dose of 2 tablets once weekly, started one week before travelling and continued for 4 weeks after returning.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Chloroquine is suitable during pregnancy and breastfeeding, however it should not be taken if you suffer with epilepsy or psoriasis. The tablets should be taken with or after food to help reduce side effects.

If you do experience side effects from Avloclor they may include nausea, diarrhoea, headache, rashes, skin itch, blurred vision, hair loss, dizziness, mood change, sun sensitivity or seizures.  As such you should not take Avloclor if you or a close relative suffers with epilepsy. Avloclor can also worsen psoriasis; people who suffer with psoriasis should avoid taking Avloclor if possible. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Avloclor should not cause a harmful interaction with any of your other current medicines. Please read the Patient Information Leaflet enclosed with your medicines for further information.

You should try to avoid taking Avloclor around the same time as indigestion or heartburn remedies containing high levels of calcium, iron or magnesium as this can reduce its effectiveness. 

Avloclor is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.  

Doxycycline 100mg Capsules
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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  • You should take one capsule every day at roughly the same time each day.
  • Doxycycline needs to be taken two days before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Doxycycline with or after food and with a full glass of water.
  • Doxycycline remains effective with a moderate alcohol intake.

Doxycycline is taken once daily. It needs to be started 2 days before travel and continued for 4 weeks after returning.

Please read the Patient Information Leaflet for side effects and additional information 

Pharmacist Tip: Doxycyline is not suitable during pregnancy or breastfeeding. Any side effects experienced can usually be helped by taking the capsules with or after food. Doxycycline can make your skin more sensitive to sunlight leading to sunburn and it reduces the effectiveness of contraceptives, so be sure to take adequate care during and after the course.

If you do experience side effects from Doxycycline they may include nausea, diarrhoea, thrush, sore tongue, and inflammation of the liver or bowel. Doxycycline can cause your skin to be more sensitive to sunlight, this means you could burn more easily in direct sunlight. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Doxycycline should not cause a harmful interaction with any of your other current medicines. Please read the Patient Information Leaflet enclosed with your medicines for further information.

You should try to avoid taking Doxycycline around the same time as foods or supplements containing high levels of calcium, iron or magnesium as this can reduce its effectiveness. This particularly applies to dairy products.

Doxycycline is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

Remember to always wear high factor sun cream or protect your skin from direct sunlight whilst taking Doxycycline. Severe sunburn can be extremely unpleasant and even dangerous.

It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.

Malaria can take up to a year to develop after you have been bitten. If you experience symptoms including headaches, night sweats and abdominal pain any time during your trip or up to one year afterwards you must see a doctor as soon as possible.

Lariam 250mg Tablets
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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Our Price: £30.90
Total trip duration in weeks: In Stock 
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  • You should take one tablet every week on the same day each week.
  • Lariam needs to be taken two and a half weeks before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Lariam with or after food.
  • Lariam remains effective with a moderate alcohol intake.

Mefloquine is the drug contained in the branded antimalarial Lariam. It has the advantage of being taken once weekly and needs to be taken 2 – 3 weeks before travel and 4 weeks after returning.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Mefloquine is not suitable in pregnancy or during breastfeeding, or for patients with epilepsy or those who will be at altitude or scuba diving. 

If you do experience side effects from Lariam they may include depression, mood changes, anxiety, confusion, hallucinations, panic attacks, restlessness, paranoia and general agitation. Lariam has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. There have been rare reports of suicidal thoughts whilst taking Lariam. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Lariam should not cause a harmful interaction with any of your other current medicines. Lariam should not be taken if you currently take carbamazepine, chloroquine, halofantrine, ketoconazole, phenobarbital, phenytoin, quinidine, quinine, rifampicin, or valproic acid (valproate). This was checked during your online consultation. Please read the Patient Information Leaflet enclosed with your medicines for further information.

Lariam is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

Remember it is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave. 

Remember, malaria can take up to a year to develop after you have been bitten. If you experience symptoms including headaches, night sweats and abdominal pain any time during your trip or up to one year afterwards you must see a doctor as soon as possible. 

You should take adequate contraceptive precautions to ensure you do not become pregnant whilst taking Lariam and for three months after you have finished the course.

Malarone 250mg/100mg Tablets
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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RRP*: £60.00
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Our Price: £51.90
Total trip duration in weeks: In Stock 
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  • You should take one tablet every day at roughly the same time each day.
  • Malarone needs to be taken 2 – 3 days before entering an area where malaria is present and continued until 7 days after leaving the malaria area.
  • You should take Malarone with or after food or milk
  • Malarone remains effective with a moderate alcohol intake.

Malarone contains the active ingredients atovaquone and proguanil, and is one of the newer treatments for malaria. It is taken once daily, 2 – 3 days before travel and continuing 1 week after returning.

 Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Malarone should not be taken if you are pregnant or breastfeeding. It is generally very well tolerated with only mild intestinal upsets and headaches reported. If side effects are experienced then taking the tablets with or after a meal may help to relieve them. 

If you do experience side effects from Malarone they may include coughing, diarrhea, dizziness, headache, loss of appetite, mouth sores, nausea, stomach pain, vomiting, or weakness. Malarone has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Malarone should not cause a harmful interaction with any of your other current medicines. Please read the Patient Information Leaflet enclosed with your medicines for further information.

Unfortunately Malarone is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

Remember it is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave. 

Remember, malaria can take up to a year to develop after you have been bitten. If you experience symptoms including headaches, night sweats and abdominal pain any time during your trip or up to one year afterwards you must see a doctor as soon as possible.

Paludrine 100mg Tablets
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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Proguanil is the active ingredient in Paludrine tablets. The dose is 2 tablets daily starting 1 week before travel and continued for 4 weeks after returning.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Proguanil is suitable to take during pregnancy and breastfeeding. The tablets should be taken with or after food to help reduce side effects.

Paludrine/Avloclor Travel Pack 250mg/100mg Tablets
Pack Size: All treatments are complete courses that include tablets for before and after your trip.
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  • You should take two Avloclor tablets every week on the same day each week.
  • You should take two Paludrine tablets every day at roughly the same time each day.
  • Paludrine/Avloclor needs to be taken one week before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Paludrine/Avloclor with or after food.
  • Paludrine/Avloclor remains effective with a moderate alcohol intake.

In areas of possible chloroquine resistance, it is combined with proguanil to ensure you are adequately protected during your travels. Choloroquine is taken as a single dose of 2 tablets once weekly and proguanil is taken as 2 tablets daily. Both tablets are started 1 week before travel and continued for 4 weeks after returning.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Chloroquine/proguanil is suitable during pregnancy and breastfeeding, however it should not be taken if you suffer with epilepsy or psoriasis. The tablets should be taken with or after food to help reduce side effects.

If you do experience side effects from Avloclor they may include nausea, diarrhoea, headache, rashes, skin itch, blurred vision, hair loss, dizziness, mood change, sun sensitivity or seizures.  As such you should not take Avloclor if you or a close relative suffers with epilepsy. Avloclor can also worsen psoriasis; people who suffer with psoriasis should avoid taking Avloclor if possible. The side effects of Paludrine can include anorexia, nausea, diarrhoea, constipation, skin itch and mouth ulcers. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Paludrine/Avloclor should not cause a harmful interaction with any of your other current medicines. Paludrine can prolong bleeding time if taken with anticoagulants such as warfarin. If you take an anticoagulant you should speak to your GP before taking Paludrine/Avloclor. Please read the Patient Information Leaflet enclosed with your medicines for further information.

You should try to avoid taking Avloclor around the same time as indigestion or heartburn remedies containing high levels of calcium, iron or magnesium as this can reduce its effectiveness. 

Paludrine/Avloclor is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods. 

 It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.

About Malaria Prevention

Malaria Prevention Background

THE Medical Online Doctor service allows anyone going travelling to an area of the world with a risk of malaria to gain access the right tablets for malaria prevention on their trip.

Malaria is tropical disease caused by plasmodium parasites. This parasite is spread to humans through the bite of an infected female anopheles mosquito. If malaria is not diagnosed and treated quickly then potentially it can be fatal. The five types of malaria causing plasmodium parasites are as follows:

  • Plasmodium falciparum: This is the most common type of malaria parasite and is found predominantly in Africa. This form of parasite causes the highest number of global deaths from malaria.
  • Plasmodium vivax: This parasite produces milder symptoms when compared with plasmodium falciparum. Plasmodium vivax is mainly found in South America and Asia.
  • Plasmodium oval: This parasite is usually found in West Africa. It is quite uncommon.
  • Plasmodium malaria: A rare parasite that is usually only found in Africa.
  • Plasmodium knowlesi: This is only found in parts of South East Asia and is very rare.

Once bitten by an infected mosquito the malaria parasite will enter the bloodstream. Once the parasites reach the liver the infection will begin to develop. From here, the infection will renter the bloodstream and begin to multiply inside the red blood cells. As the infection grows it will periodically cause the red bloods cells to burst, releasing more parasites into the blood stream. It’s the bursting of the red blood cells that cause the fever symptoms of malaria.

On average it takes between 7-18 days after the initial mosquito bite for the infection to incubate and present the sufferer with any symptoms. However, in some cases it can take up to a year before any symptoms present so travellers should be vigilant for symptoms after returning from their trip.

Our country-by-country breakdown allows you to find which malaria prevention is suitable for your trip in one easy step. Using our innovative Travel Centre you can access all the information and purchase all the products you need to look after your health abroad.

Malaria Prevention Symptoms

The initial symptoms of malaria resemble the flu. The sufferer will have a high temperature or fever, chills, sweats, vomiting and headache. This can often occur in cycles where for the first hour you will feel cold and shivery. Then for the next two to six hours you will suffer a fever accompanied by severe sweating. Diarrhoea and muscle pains can also be symptoms of malaria, however not everyone experiences these.

Sustaining an infection from the most common malaria parasites can quickly lead to severe, life threatening complications. This can include problems with breathing and even organ failure. This is why treatment should be promptly sought if an infection is suspected.

As stated above, if any of the symptoms of malaria are experienced for up to a year (and especially in the first 3 months) on returning from an area with a malaria risk, you should see your GP and ensure you mention your recent travel.

Malaria Prevention Diagnosis

If you suspect having malaria or are experiencing any of the symptoms after having recently travelled to an area where malaria is found, then it is important to seek medical advice immediately. A delay in diagnoses and treatment can prove fatal. In fact, in The USA this delay is one of the leading causes of deaths in malaria patients.

Malaria will typically be diagnosed based on a patients recent travel history coupled with the presenting symptoms. However, for conclusive results a laboratory test must demonstrate the presence of the malaria parasites and their components. This diagnoses can be performed using a microscopic analysis, where a blood smear can be examined under a microscope in order to identify the presence of the malaria parasite. This is usually the preferred and most reliable means of diagnoses.

Another method of diagnosing malaria includes the Antigen tests. This is usually reserved for areas where microscopic analysis isn’t practical. These commercially available antigen tests are sometimes referred to as ‘Malaria Rapid Detection Tests’. It involves a finger-stick that samples a drop of blood. To complete the test usually take between 15-20 minutes.

Malaria Prevention Treatment

Taking malaria tablets when you are visiting an area where malaria is present is very important. They should always be taken exactly as instructed by the prescriber and combined with measures to avoid bites.

There are multiple regimes of malaria tablets due to differing resistance in different parts of the world. The advice on which regimen to follow for a specific area is constantly updated and you should never assume that a tablet that you have taken before for a specific area is still appropriate unless advised by a healthcare professional.

You can buy the following malaria tablets from our Online Doctor: Malarone, atovaquone/proguanil (generic Malarone), mefloquine (Lariam), doxycycline, chloroquine, proguanil, and cholorquone/proguanil tablets.

To help find out which malaria tablets are required for your trip, take a look at our Travel Centre each country page contains specific information about the healthcare requirements for your trip. You can also confirm your requirements at Fit For Travel, where you can get detailed information on the required antimalarials and vaccines.

If you are unsure which malaria tablets to take during your trip due to multiple regimens being recommended, ensure you read all the product information before to ensure you understand the dose and possible side effects of each. In areas where one of either Lariam (mefloquine) or doxycycline or Malarone (atovaquone/proguanil) are recommended, you are generally least likely to experience side effects with Malarone (or generic atovaquone/proguanil). However, Malarone must be taken daily so this must also be considered as it must be taken regularly to get maximal protection against malaria.

When travelling to an area where malaria is found it is strongly advised to take the appropriate malaria tablets to ward off potential infection. There are various forms and types of antimalarial medication and knowing which one is suitable will depend on these factors:

  • Your destination
  • Medication you are currently taking and your medical history
  • Any relevant family medical history
  • Your age
  • Whether you are pregnant

As different malaria parasites are found in different areas, choosing the right drug is vital in providing an effective means of protection. This is because some of the medicines are more effective at combating certain types of parasites than others. The main types of antimalarial treatments are as follows:

  • Malarone (and generic Atovaquone & Proguanil)

Malarone contains atovaquone & proguanil and is available as the brand ‘Malarone’ or as a generic tablet simply called Atovaquone & Proguanil. This generic form is sometimes referred to as ‘generic Malarone’. The dose is one tablet every day, starting 2 days before entering the malaria area and continuing until 7 days after leaving. Malarone is the most expensive antimalarial tablet, however it tends to the best tolerated with the least side effects. Buying generic Malarone (Atovaquone & Proguanil) can help to make them more affordable.

A child’s dose may differ to that of an adult and will be dependant of age and weight. Malarone is available in a paediatric strength, making these differing doses easier to achieve. Malarone is not recommended if you are pregnant or breastfeeding or if you suffer from severe kidney disease.

  • Doxycycline

Doxycycline comes in a capsule and a dispersible tablet (Vibramycin-D). The dose is for one capsule or tablet to be taken every day, starting 2 days prior to entering the malaria area and continuing for 4 weeks after leaving. Doxycycline is a cheaper option for antimalarial cover, however it can cause the skin to become sensitive to sunlight meaning you will burn very quickly. For those with pale skin, this may not be suitable in more tropical climates where malaria is present. It is advisable for anyone taking doxycycline to use high factor suncream (SPF 50+) when going out in the sun.

Doxycycline Capsules and Vibramycin-D Tablets are not recommended for pregnant or breastfeeding women or for children under the age of twelve years.

  • Lariam (Mefloquine)

Lariam tablets contain the drug mefloquine. The adult dose is to take one tablet weekly, starting three weeks before entering the malaria area and continuing for four weeks after leaving. Lariam tablets are not recommended if you suffer from epilepsy, seizures or mental health conditions, such as depression.

  • Chloroquine & Proguanil

Chloroquine & Proguanil can be used in combination or separately to prevent malaria, however they aren’t as commonly used these days as they are considered ineffective against the most common form of malarial parasite (plasmodium falciparum). However, Chloroquine and/or Proguanil will still be recommended in such areas where the plasmodium falciparum is less common. These areas include India and Sri Lanka.

Many of the above antimalarial treatments can be used to treat as well as prevent malaria. If an infection has been diagnosed then rapid, appropriate treatment should ensure a full recovery. You should never try to treat malaria with your preventative treatment. Malaria is a medical emergency that requires rapid, professional treatment.

Important Information

When selecting the quantity of malaria tablets required please round your trip length up to the nearest full week. For example a 10-day trip would be 2 weeks and and a 30-day trip would be 5 weeks.

All treatments include tablets for before and after your trip. For example, if you select you are going on a 3 week trip, you will receive 30 tablets to cover 2 days before, during and 7 days after your trip.

 

Malaria Prevention Prevention

Malaria can be prevented should the appropriate precautions be taken. Using the ABCD approach can help reduce the risk of contracting the infection.

  • Awareness of risk: research whether your destination carries a risk of malaria.
  • Bite prevention: Avoid mosquito bites by using insect repellents (containing 50% DEET), mosquito nets and long, loose clothing. Examples of available products include; Jungle Formula Sprays and Plug-Ins, Lifesystems Mosquito Nets and protection sprays. Wear loose-fitting clothing that covers the arms, legs and body, especially at night when the mosquitos are more prone to biting.
  • Check whether you need to take antimalarial prevention tablets: If needed, make sure the correct medicine is taken at the correct dose and ensure the course in completed as directed.
  • Diagnoses: If malaria symptoms should develop, seek medical attention immediately. This will include up to a year after leaving a malaria zone.

To summarise the actions you can take to help prevent malaria whilst on your travels:

  • Avoid outings at night – Anopheles mosquitoes are night feeders. They typically remain active from dusk to dawn.
  • Use strong insect repellents – If you must step out after dark, use a strong mosquito repellent containing DEET.
  • Dress from head to toe – Full-sleeved cotton shirts and full-length pants are the preferred attire despite the heat and humidity. Loose fitting clothing is best to prevent being bitten through the material.
  • Use mosquito repellents inside the house – Burning coils or vaporizing mats containing mosquito repellents help keep these pests away.
  • Sleep under protective nets impregnated with insecticides – Even when repellents are used inside the house and on the person, everyone should sleep under protective nets that have been treated with insecticides.
  • Prevent malaria through chemoprophylaxis – Anti-malarial drugs can be used as a preventive measure as they help suppress the parasite growth and their multiplication in the blood.

 

*RRP is based on the highest price found for a comparable online service found on 04/09/14.

THE Medical Online Doctor service is owned and operated by Total Health Ethos Limited (Company Reg. 6170784). All orders are fulfilled by our pharmacy partners, BSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products. For more information see our policies and terms and conditions at the bottom of every page. © 2017 Total Health Ethos Limited. All rights reserved.
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